Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646137 | 0.90 | HTR1A (0.60) | HTR1AHTR7 | |
| SCHEMBL9647583 | 0.89 | KDM4E (0.58) | HTR1AHTR7 | |
| SCHEMBL9644779 | 0.89 | HTR1A (0.48) | HTR1AHTR7 | |
| SCHEMBL9645728 | 0.86 | ALDH1A1 (0.52) | DRD2DRD4HTR1ADRD3HTR7 | |
| SCHEMBL9645787 | 0.85 | HTR1A (0.50) | HTR1AHTR7 | |
| SCHEMBL9644860 | 0.85 | KDM4E (0.49) | DRD4HTR1AHTR7 | |
| SCHEMBL9644844 | 0.84 | TSHR (0.51) | DRD2DRD4HTR1AHTR7 | |
| SCHEMBL9589251 | 0.83 | KDM4E (0.52) | — | |
| SCHEMBL9646526 | 0.83 | NOTUM (0.44) | DRD2HTR1AHTR7DRD1 | |
| SCHEMBL9646894 | 0.83 | HTR1A (0.70) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |