Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.55 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151380 | 0.94 | NPSR1 (0.59) | L3MBTL1ATMTDP1CA1CA2 | |
| SCHEMBL19601226 | 0.85 | NPSR1 (0.51) | L3MBTL1ATMTDP1CA1CA2 | |
| SCHEMBL29556844 | 0.84 | AKR1C3 (0.56) | L3MBTL1CA1CA2ALDH1A1RAB9A | |
| SCHEMBL399246 | 0.84 | AKR1C3 (0.56) | L3MBTL1CA1CA2ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL4563542 | 0.82 | AKR1C3 (0.54) | L3MBTL1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL14982062 | 0.82 | MAPK13 (0.74) | L3MBTL1ATMTDP1CA1CA2 | |
| SCHEMBL24166608 | 0.82 | L3MBTL1 (0.65) | L3MBTL1ATMTDP1CA1CA2 | |
| SCHEMBL8666599 | 0.82 | MAPK13 (0.67) | L3MBTL1ATMTDP1PDK1PDK2 | |
| SCHEMBL11031257 | 0.81 | ALDH1A1 (0.71) | L3MBTL1ATMTDP1CA1CA2 | |
| SCHEMBL13001967 | 0.81 | KMT2A (0.67) | L3MBTL1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194546-A1 | Pyrido-, Pyrazo- and Pyrimido-Pyrimidine Derivatives as mTOR Inhibitors | KUDOS PHARMACEUTICALS LIMITED (GB) | 2008-08-14 | — | — | US | disclosed |
| WO-1992017476-A1 | BENZOYLPHENYL PYRIDINYLTHIAZOLIDINE COMPOUNDS AS PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5120751-A | Platelet activating factor antagonist | ABBOTT LABORATORIES (US) | 1992-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194546-A1 | Pyrido-, Pyrazo- and Pyrimido-Pyrimidine Derivatives as mTOR Inhibitors | RPS6KB1, RPS6KA1, RPS3A | L3MBTL1 1898/4885ATM 3619/4885TDP1 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.