Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.57 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14289823 | 0.86 | NPC1 (0.66) | MEN1KMT2AEPHX2RAB9ACA2 | |
| SCHEMBL23072523 | 0.84 | ALDH1A1 (0.68) | L3MBTL1MEN1KMT2APDK1PDK2 | |
| SCHEMBL4371367 | 0.84 | KMT2A (0.74) | MEN1KMT2AGAARAB9ATDP1 | |
| SCHEMBL11031257 | 0.83 | ALDH1A1 (0.71) | L3MBTL1MEN1KMT2AGAAPDK1 | |
| SCHEMBL12060819 | 0.83 | HDAC8 (0.58) | MEN1KMT2ANPSR1RAB9ASIRT1 | |
| SCHEMBL12096453 | 0.82 | L3MBTL1 (0.68) | L3MBTL1MEN1KMT2AGAAPDK1 | |
| SCHEMBL17589369 | 0.82 | KMT2A (0.66) | MEN1KMT2AEPHX2NPSR1RAB9A | |
| SCHEMBL9645083 | 0.82 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAAPDK1 | |
| SCHEMBL14289778 | 0.81 | PARP1 (0.68) | MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL7745302 | 0.81 | KCNK3 (0.79) | L3MBTL1MEN1KMT2AGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022003712-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-01-06 | — | — | WO | disclosed |