SCHEMBL8666599

SCHEMBL8666599

CNc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 2/20 0.67
MAPK12 P53778 2/20 0.67
MAPK11 Q15759 2/20 0.67
MAPK14 Q16539 2/20 0.67
ALDH1A1 P00352 7/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
RAB9A P51151 5/20 0.62
NPC1 O15118 2/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
HPGD P15428 4/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
HTT P42858 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
SRD5A2 P31213 1/20 0.58
LMNA P02545 1/20 0.58
FFAR1 O14842 1/20 0.56
TSHR P16473 1/20 0.54
MAPT P10636 2/20 0.53
ATM Q13315 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52136 0.91 ALDH1A1 (0.52) MAPK13MAPK12MAPK11MAPK14ALDH1A1
Benzophenone SCHEMBL329684 0.84 ALDH1A1 (0.78) MAPK13MAPK12MAPK11MAPK14ALDH1A1
Benzophenone SCHEMBL28325902 0.84 ALDH1A1 (0.78) MAPK13MAPK12MAPK11MAPK14ALDH1A1
Benzophenone SCHEMBL28328302 0.84 ALDH1A1 (0.78) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL25652847 0.83 ALDH1A1 (0.70) ALDH1A1RAB9ANPC1SMN1; SMN2SRD5A2
SCHEMBL23268506 0.82 TSHR (0.59) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL14283579 0.82 TSHR (0.59) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL29196087 0.82 MAPK13 (0.95) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL9645083 0.82 L3MBTL1 (0.63) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL22212597 0.81 ACHE (0.54) RAB9ANPC1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0123493-A1 Photochemical conversion and storage of light energy by photoisomerization of compounds such as norbornadiene and its derivatives THE STANDARD OIL COMPANY (US) 1984-10-31 EP claimed
US-12319661-B2 Polycyclic compound EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2025-06-03 US disclosed
CN-115819359-B Blue light preventing compound, preparation method and composition thereof 江苏裕事达新材料科技有限责任公司 2025-04-18 CN disclosed
CN-115745970-B Polycyclic compound, preparation method and membrane 江苏裕事达新材料科技有限责任公司 2024-12-13 CN disclosed
CN-118359321-A Application of deinococcus in degradation of malachite green wastewater 扬州工业职业技术学院 2024-07-19 CN disclosed
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 HIROSHIMA UNIVERSITY (JP) 2024-01-25 US disclosed
US-20240025873-A1 METHOD FOR PRODUCING KETONE DERIVATIVE TOKUYAMA CORPORATION (JP) 2024-01-25 US disclosed
US-20240025873-A1 METHOD FOR PRODUCING KETONE DERIVATIVE TOKUYAMA CORPORATION (JP) 2024-01-25 US disclosed
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 HIROSHIMA UNIVERSITY (JP) 2024-01-25 US disclosed
US-11845824-B2 Same novel polymer and organic light emitting device comprising the same LG CHEM, LTD. 2023-12-19 US disclosed
US-20100273842-A1 AMINE DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY AND THE USES THEREOF SHIONOGI & CO., LTD. (JP) 2010-10-28 US disclosed
US-20100267945-A1 AMINE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY SHIONOGI & CO., LTD. (JP) 2010-10-21 US disclosed
WO-2008067928-A1 UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE ISDIN S.A. (ES) 2008-06-12 WO disclosed
US-5792589-A ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-08-11 US disclosed
US-4163810-A Ultraviolet curable powder paints SCM CORPORATION (US) 1979-08-07 US disclosed
US-4129488-A Ultraviolet curable epoxy-polyester powder paints SCM CORPORATION (US) 1978-12-12 US disclosed
US-4105518-A POLYMER CONTAINING ACRYLYL, ACRYLAMIDE OR ALLYL UNSATURATED GROUPS, REACTED WITH SECONDARY AMINE AND NEUTRALIZED, SENSITIZER SCM CORPORATION (US) 1978-08-08 US disclosed
US-4052280-A PHOTOSENTIZER IN BACKBONE OF POLYMER SCM CORPORATION (US) 1977-10-04 US disclosed
US-4040925-A PAINTS; CHEMICALLY BONDED ULTRAVIOLET SENSITIZER SCM CORPORATION (US) 1977-08-09 US disclosed
US-4039414-A ACRYLYL, ACRYLAMIDE, OR ALLYL POLYMERS, BENZALDEHYDE SENSITIZER SCM CORPORATION (US) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100273842-A1 AMINE DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY AND THE USES THEREOF NPY5R, NPY1R, NPY2R MAPK13 977/4885MAPK12 1267/4885MAPK11 1048/4885
US-20100267945-A1 AMINE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY NPY5R, NPY1R, NPY2R MAPK13 1651/4885MAPK12 2240/4885MAPK11 1558/4885
US-12319661-B2 Polycyclic compound CUTA, CDH1, DSG1 MAPK13 2527/4885MAPK12 3899/4885MAPK11 2393/4885
US-20240025873-A1 METHOD FOR PRODUCING KETONE DERIVATIVE HSD17B7, BCKDK, KARS1 MAPK13 2055/4885MAPK12 1702/4885MAPK11 1502/4885
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 PIN1, ACE2, ACE MAPK13 304/4885MAPK12 167/4885MAPK11 352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.