Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645969 | 0.82 | ALDH1A1 (0.43) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9647043 | 0.80 | GAA (0.44) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9670988 | 0.78 | KDM4E (0.47) | KMT2ALMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9647098 | 0.76 | KDM4E (0.41) | KMT2ASMN1; SMN2ALDH1A1MEN1RXFP1 | |
| SCHEMBL9466405 | 0.76 | KDM4E (0.46) | KMT2ALMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9647155 | 0.76 | KMT2A (0.53) | KMT2ALMNAPDE4APDE4BPDE4C | |
| SCHEMBL5109666 | 0.74 | L3MBTL1 (0.46) | KMT2ALMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9647053 | 0.74 | TSHR (0.41) | KMT2ASMN1; SMN2ALDH1A1MEN1NPSR1 | |
| SCHEMBL9646200 | 0.73 | SMN1; SMN2 (0.42) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9377264 | 0.73 | L3MBTL1 (0.48) | KMT2ALMNASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |