Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646352 | 0.83 | NR1H2 (0.40) | KMT2AALDH1A1LMNAMEN1PDE4A | |
| SCHEMBL9646337 | 0.80 | PARP1 (0.44) | KMT2ALMNAMEN1MAPT | |
| SCHEMBL31667524 | 0.79 | P2RX4 (0.49) | KMT2AALDH1A1SMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL9645136 | 0.76 | KMT2A (0.55) | KMT2ANOX4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30024568 | 0.72 | ALDH1A1 (0.64) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL5387829 | 0.72 | ALDH1A1 (0.64) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL31667699 | 0.72 | POLB (0.48) | KMT2AALDH1A1MEN1 | |
| SCHEMBL16137947 | 0.71 | MAPT (0.44) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL5005428 | 0.71 | MAPT (0.44) | KMT2AALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL6676703 | 0.69 | MAPT (0.55) | KMT2AALDH1A1SMN1; SMN2MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |