Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645136 | 0.82 | KMT2A (0.55) | ALDH1A1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL9670988 | 0.78 | KDM4E (0.47) | ALDH1A1HTTLMNASMN1; SMN2KDM4E | |
| SCHEMBL11380104 | 0.75 | KDM4E (0.67) | ALDH1A1HTTLMNASMN1; SMN2KDM4E | |
| SCHEMBL9466405 | 0.73 | KDM4E (0.46) | ALDH1A1HTTLMNASMN1; SMN2KDM4E | |
| SCHEMBL9670940 | 0.73 | L3MBTL1 (0.65) | ALDH1A1KDM4EACHEMEN1KMT2A | |
| SCHEMBL9647043 | 0.73 | GAA (0.44) | ALDH1A1HTTLMNASMN1; SMN2KDM4E | |
| SCHEMBL9645862 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13816435 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL9647098 | 0.72 | KDM4E (0.41) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL9647004 | 0.72 | AKR1B1 (0.46) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |