Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | DPEP1 | P16444 | 7/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647093 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KMT2AGRIK1GRIK2METAP2 | |
| SCHEMBL9647060 | 0.84 | METAP1 (0.46) | ALDH1A1KMT2AGRIK1GRIK2SLC1A2 | |
| SCHEMBL9645168 | 0.84 | METAP1 (0.54) | DPEP1LAP3ANPEPERAP2METAP1 | |
| SCHEMBL9646994 | 0.83 | DPEP1 (0.49) | DPEP1LAP3ANPEPERAP2METAP1 | |
| SCHEMBL9645181 | 0.82 | LAP3 (0.57) | GRIK1GRIK2SLC1A2SLC1A1LAP3 | |
| SCHEMBL8737263 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AGRIK1GRIK2METAP2 | |
| SCHEMBL8737248 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AGRIK1GRIK2METAP2 | |
| SCHEMBL8735264 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AGRIK1GRIK2METAP2 | |
| SCHEMBL28807909 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AGRIK1GRIK2METAP2 | |
| SCHEMBL5372466 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AGRIK1GRIK2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | claimed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | claimed |
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |