Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.46 |
| ▸ | G6PD | P11413 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644523 | 0.83 | ALOX5 (0.50) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL9645716 | 0.79 | ALOX5 (0.46) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL14045038 | 0.75 | MEN1 (0.56) | BLMCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9646977 | 0.74 | ALOX5 (0.51) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL9644469 | 0.72 | ALOX5 (0.56) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL21765696 | 0.71 | POLB (0.57) | BLMCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9644628 | 0.68 | ALOX5 (0.56) | ALOX5CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL9645360 | 0.67 | DDB1 (0.53) | ALOX5G6PDALOX15ALOX12PTGS1 | |
| SCHEMBL21765698 | 0.66 | POLB (0.68) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL12781874 | 0.66 | MAPT (0.70) | BLMSMN1; SMN2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |