Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644526 | 0.82 | KMT2A (0.39) | CFTRMAPTALOX5MEN1KMT2A | |
| SCHEMBL9645722 | 0.78 | ELANE (0.35) | LMNACFTRELANEHTTALOX5 | |
| SCHEMBL9646990 | 0.73 | ELANE (0.37) | LMNACFTRELANEALOX5SMN1; SMN2 | |
| SCHEMBL10512770 | 0.71 | LMNA (0.39) | LMNABLMCFTRMAPTHTT | |
| SCHEMBL9644474 | 0.71 | GSK3A (0.41) | LMNACFTRMAPTHTTALOX5 | |
| SCHEMBL9645190 | 0.65 | ALOX5 (0.46) | LMNABLMELANEMAPTHTT | |
| SCHEMBL10514294 | 0.64 | ALOX5 (0.40) | ELANEALOX5GAAL3MBTL1ALDH1A1 | |
| SCHEMBL9644496 | 0.60 | KMT2A (0.41) | CES1MAPTHTTMEN1KMT2A | |
| SCHEMBL14045038 | 0.60 | MEN1 (0.56) | LMNABLMMAPTHTTTSHR | |
| SCHEMBL12781874 | 0.60 | MAPT (0.70) | LMNABLMMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |