Sugi Predict

Sugi Predict / Compounds / SCHEMBL9645533

SCHEMBL9645533

SCHEMBL9645533

CC1(C)CC(CCCCNc2nc(NCCCCC3CC(C)(C)N(CCO)C(C)(C)C3)nc(NCCCCC3CC(C)(C)N(CCO)C(C)(C)C3)n2)CC(C)(C)N1CCO

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.37
▸ KCNH3 Q9ULD8 3/20 0.33
▸ SLC29A1 Q99808 1/20 0.32
▸ EHMT2 Q96KQ7 1/20 0.31
▸ EHMT1 Q9H9B1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9645849 0.84 FLT3 (0.35) KMT2AKCNH3
SCHEMBL4813196 0.83 KMT2A (0.34) KMT2AKCNH3
SCHEMBL9373101 0.83 FLT3 (0.37) KMT2AKCNH3
SCHEMBL9427851 0.81 KMT2A (0.40) KMT2AKCNH3SLC29A1EHMT2EHMT1
SCHEMBL9646106 0.80 GBA1 (0.30) —
SCHEMBL9429384 0.80 KMT2A (0.42) KMT2AKCNH3SLC29A1EHMT2EHMT1
SCHEMBL6299669 0.78 KMT2A (0.36) KMT2ASLC29A1
SCHEMBL9741341 0.78 KMT2A (0.31) KMT2A
SCHEMBL714018 0.78 KMT2A (0.43) KMT2A
SCHEMBL9428703 0.78 KMT2A (0.49) KMT2AKCNH3SLC29A1EHMT2EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0107615-B1 POLYOLEFINS STABILIZED BY BIS OR TRIS (POLYALKYLPIPERIDINYL-AMINO) 1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1992-10-28 — — EP claimed
US-5102927-A Againts oxidative and light induced degradation CIBA-GEIGY CORPORATION (US) 1992-04-07 — — US claimed
EP-0107615-B1 POLYOLEFINS STABILIZED BY BIS OR TRIS (POLYALKYLPIPERIDINYL-AMINO) 1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1992-10-28 — — EP disclosed