Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022080 | 0.93 | KMT2A (0.45) | KMT2AGAAKDM4E | |
| SCHEMBL9645849 | 0.86 | FLT3 (0.35) | KMT2AKCNH3 | |
| SCHEMBL9373101 | 0.85 | FLT3 (0.37) | KMT2AKCNH3 | |
| SCHEMBL9741341 | 0.83 | KMT2A (0.31) | KMT2A | |
| SCHEMBL9645533 | 0.83 | KMT2A (0.37) | KMT2AKCNH3 | |
| SCHEMBL7713694 | 0.82 | KMT2A (0.33) | KMT2AGAAKDM4E | |
| SCHEMBL714018 | 0.80 | KMT2A (0.43) | KMT2A | |
| SCHEMBL9427851 | 0.80 | KMT2A (0.40) | KMT2AGAAKCNH3 | |
| SCHEMBL9646106 | 0.79 | GBA1 (0.30) | — | |
| SCHEMBL3141095 | 0.79 | KMT2A (0.45) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391949-B1 | — | — | None | — | — | US | disclosed |
| US-7390904-B2 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-06-24 | — | — | US | disclosed |
| EP-1644329-A1 | HYDROGEN PEROXIDE CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-HYDROCARBYLOXYAMINES | Ciba SC Holding AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| US-6872832-B2 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-03-29 | — | — | US | disclosed |
| US-20050014948-A1 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-20 | — | — | US | disclosed |
| WO-2005005388-A1 | HYDROGEN PEROXIDE CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-HYDROCARBYLOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-01-20 | — | — | WO | disclosed |
| US-6638997-B2 | Used for stabilizing polyolefin and automotive coating formulation against the deleterious effects of oxidative, thermal and actinic radiation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-28 | — | — | US | disclosed |
| US-6586507-B2 | For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2003-06-26 | — | — | US | disclosed |
| US-6420562-B2 | OXIDATION, HEAT AND RADIATION RESISTANCE | CIBA SPECIALITY CHEMICALS CORPORATION | 2002-07-16 | — | — | US | disclosed |
| US-6380389-B2 | FOR POLYOLEFINS AND AUTOMOTIVE COATINGS; LIGHT, HEAT, OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-30 | — | — | US | disclosed |
| US-6376584-B1 | OXIDATION RESISTANCE, HEAT RESISTANCE, PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-23 | — | — | US | disclosed |
| US-20020040145-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2002-04-04 | — | — | US | disclosed |
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-25 | — | — | US | disclosed |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-18 | — | — | US | disclosed |
| US-20010020099-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-09-06 | — | — | US | disclosed |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-30 | — | — | US | disclosed |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-23 | — | — | US | disclosed |
| US-6271377-B1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-08-07 | — | — | US | disclosed |
| US-6166212-A | Process for the synthesis of N-(hydroxyalkoxy) substituted hindered amine stabilizers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040145-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GAA 1582/4885KDM4E 1548/4885 |
| US-20050014948-A1 | Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines | HAO2, SOD1, PPOX | KMT2A 924/4885GAA 2096/4885KDM4E 2770/4885 |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GAA 1582/4885KDM4E 1548/4885 |
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GAA 1582/4885KDM4E 1548/4885 |
| US-20010020099-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GAA 1582/4885KDM4E 1548/4885 |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, POLH, OGFOD1 | KMT2A 615/4885GAA 1590/4885KDM4E 679/4885 |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GAA 1582/4885KDM4E 1548/4885 |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GAA 1582/4885KDM4E 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.