Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645787 | 0.89 | HTR1A (0.50) | ALDH1A1HTR1AHTR7ADORA2AKDM4E | |
| SCHEMBL9646137 | 0.87 | HTR1A (0.60) | ALDH1A1HTR1AHTR7KDM4E | |
| SCHEMBL9646338 | 0.86 | DRD2 (0.52) | HTR1AHTR7DRD2OPRK1DRD3 | |
| SCHEMBL9647583 | 0.86 | KDM4E (0.58) | HTR1AHTR7HTR2AMAPTKMT2A | |
| SCHEMBL9644779 | 0.86 | HTR1A (0.48) | ALDH1A1HTR1AHTR7KMT2AKDM4E | |
| SCHEMBL9647687 | 0.82 | HTR1A (0.65) | HTR1AHTR7DRD2HTR2ADRD3 | |
| SCHEMBL9644860 | 0.82 | KDM4E (0.49) | ALDH1A1HTR1AHTR7DRD4KDM4E | |
| SCHEMBL9592125 | 0.82 | KDM4E (0.54) | ALDH1A1DRD2DRD4KDM4E | |
| SCHEMBL9589251 | 0.81 | KDM4E (0.52) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9646894 | 0.81 | HTR1A (0.70) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |