Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 4/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646137 | 0.90 | HTR1A (0.60) | HTR1AHTR7KDM4EALDH1A1 | |
| SCHEMBL9645728 | 0.89 | ALDH1A1 (0.52) | HTR1AADORA2AHTR7KDM4EALDH1A1 | |
| SCHEMBL9646338 | 0.85 | DRD2 (0.52) | HTR1AHTR7 | |
| SCHEMBL9644779 | 0.85 | HTR1A (0.48) | HTR1AHTR7KDM4EALDH1A1 | |
| SCHEMBL9647583 | 0.85 | KDM4E (0.58) | HTR1AHTR7KDM4E | |
| SCHEMBL9646894 | 0.84 | HTR1A (0.70) | HTR1AHTR7 | |
| SCHEMBL9644860 | 0.81 | KDM4E (0.49) | HTR1AHTR7KDM4EALDH1A1 | |
| SCHEMBL9645757 | 0.81 | NPC1 (0.53) | HTR1AKDM4EALDH1A1 | |
| SCHEMBL9645860 | 0.80 | HTR1A (0.55) | HTR1AHTR7KDM4EALDH1A1 | |
| SCHEMBL9589251 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |