Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645934 | 0.90 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL10581986 | 0.85 | KDM4E (0.53) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL7523007 | 0.84 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL5480836 | 0.81 | WDR5 (0.56) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL7258663 | 0.81 | MYC (0.38) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL29572861 | 0.80 | SLC16A3 (0.44) | MAPTALDH1A1KDM4EGAACYP3A4 | |
| SCHEMBL189571 | 0.80 | SLC16A3 (0.44) | MAPTALDH1A1KDM4EGAACYP3A4 | |
| SCHEMBL3966511 | 0.80 | MYC (0.37) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL998376 | 0.77 | CYP1A2 (0.46) | MAPTALDH1A1KDM4ETDP1GAA | |
| SCHEMBL712805 | 0.77 | WDR5 (0.51) | MAPTALDH1A1KDM4ETDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106762-A | Hydrophilic oligopeptides containing luminescent or fluorescent labels and metal or ammonium salt groups; immunoassay; water solubility; sensitivity | GEORGETOWN UNIVERSITY (US) | 1992-04-21 | — | — | US | disclosed |