SCHEMBL998376

SCHEMBL998376

NNC(=O)c1c(C(=O)O)ccc(C(=O)O)c1C(=O)NN

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
ALDH1A1 P00352 6/20 0.45
GFER P55789 2/20 0.45
MYC P01106 1/20 0.45
MAPT P10636 7/20 0.44
KDM4E B2RXH2 6/20 0.44
TDP1 Q9NUW8 3/20 0.42
CYP3A4 P08684 3/20 0.41
MPO P05164 2/20 0.41
KDM5A P29375 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
HIF1A Q16665 1/20 0.41
OGG1 O15527 1/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALOX15 P16050 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3727402 0.92 ALDH1A1 (0.44) CYP1A2ALDH1A1GFERMYCMAPT
SCHEMBL1000202 0.86 ALDH1A1 (0.48) ALDH1A1GFERMAPTKDM4EALOX15
SCHEMBL28484554 0.80 G6PD (0.53) ALDH1A1GFERMAPTKDM4ETDP1
SCHEMBL5480836 0.80 WDR5 (0.56) CYP1A2ALDH1A1MAPTKDM4ETDP1
SCHEMBL7523007 0.77 ALDH1A1 (0.51) ALDH1A1GFERMAPTKDM4ETDP1
SCHEMBL8726695 0.77 ALDH1A1 (0.42) ALDH1A1GFERMYCMAPTKDM4E
SCHEMBL9645930 0.77 MAPT (0.48) ALDH1A1GFERMYCMAPTKDM4E
SCHEMBL2678880 0.76 MYC (0.49) ALDH1A1GFERMYCMAPTKDM4E
SCHEMBL400122 0.74 ALDH1A1 (0.64) CYP1A2ALDH1A1MAPTKDM4ECYP3A4
SCHEMBL31277172 0.74 ALDH1A1 (0.64) CYP1A2ALDH1A1MAPTKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436084-B2 Aqueous coating composition and method for forming multilayer coating film KANSAI PAINT CO., LTD. (JP) 2013-05-07 US disclosed
US-20110117378-A1 AQUEOUS COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO., LTD. (JP) 2011-05-19 US disclosed
US-7868102-B2 Method for producing a film of an aromatic amide oxadiazole polymer containing an oxadiazole structure and the film so produced TORAY INDUSTRIES, INC. (JP) 2011-01-11 US disclosed
EP-1602680-B1 AROMATIC POLYMER, FILM, ELECTROLYTE MEMBRANE AND SEPARATOR TORAY INDUSTRIES (JP) 2010-12-22 EP disclosed
EP-2258746-A2 A method for producing an aromatic polymer, film, electrolyte membrane and separator Toray Industries, Inc. (JP) 2010-12-08 EP disclosed
WO-2010007891-A1 AQUEOUS COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO., LTD. (JP) 2010-01-21 WO disclosed
US-20100016521-A1 Method for producing a film of an aromatic amide oxadiazole polymer containing an oxadiazole structure and the film so produced MORIYAMA HIDEKI 2010-01-21 US disclosed
US-20090182171-A1 Compound having oxadiazole structure and a dehydration-cyclization method for producing the same MORIYAMA HIDEKI 2009-07-16 US disclosed
US-7511112-B2 Aromatic polymer, film, electrolyte membrane and separator TORAY INDUSTRIES, INC. (JP) 2009-03-31 US disclosed
US-20060204812-A1 Aromatic polymer, film, electrolyte membrane and separator MORIYAMA HIDEKI 2006-09-14 US disclosed
EP-1602680-A1 AROMATIC POLYMER, FILM, ELECTROLYTE MEMBRANE AND SEPARATOR TORAY INDUSTRIES, INC. (JP) 2005-12-07 EP disclosed
WO-2004003044-A2 DYNAMERS: POLYMERIC MATERIALS EXHIBITING REVERSIBLE FORMATION AND COMPONENT EXCHANGE LEHN JEAN-MARIE (FR) 2004-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182171-A1 Compound having oxadiazole structure and a dehydration-cyclization method for producing the same OGFOD1, ODC1, OTC CYP1A2 1214/4885ALDH1A1 973/4885GFER 1154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.