Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | MMP9 | P14780 | 6/20 | 0.43 |
| ▸ | MMP8 | P22894 | 6/20 | 0.43 |
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646074 | 0.94 | CCKBR (0.44) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL9646092 | 0.88 | LMNA (0.48) | ALDH1A1CCKBRCCKARNFE2L2 | |
| SCHEMBL9644787 | 0.86 | MMP13 (0.39) | ALDH1A1RAB9A | |
| SCHEMBL9647519 | 0.84 | CCKBR (0.50) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL9645617 | 0.81 | TRPV1 (0.39) | TRPV1ALDH1A1CA12CA7CA9 | |
| SCHEMBL9645572 | 0.79 | CCKBR (0.57) | ALDH1A1CCKBRCCKAR | |
| SCHEMBL9646148 | 0.77 | CCKAR (0.62) | ALDH1A1CCKBRCCKAR | |
| SCHEMBL9617409 | 0.75 | CCKBR (0.43) | TRPV1ALDH1A1CA12CCKBRCCKAR | |
| SCHEMBL9645604 | 0.75 | CCKBR (0.44) | TRPV1ALDH1A1CCKBRCCKAR | |
| SCHEMBL9559024 | 0.74 | CCKBR (0.46) | MMP1ALDH1A1CA12CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |