Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 1/20 | 0.62 |
| ▸ | CCKBR | P32239 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645572 | 0.93 | CCKBR (0.57) | CCKARCCKBRLMNACYP3A4CYP2C9 | |
| SCHEMBL9646092 | 0.87 | LMNA (0.48) | CCKARCCKBRLMNACYP3A4CYP2C9 | |
| SCHEMBL9558862 | 0.86 | CCKBR (0.51) | CCKARCCKBRALDH1A1 | |
| SCHEMBL9647519 | 0.86 | CCKBR (0.50) | CCKARCCKBRLMNACYP3A4CYP2C9 | |
| Water SCHEMBL9559012 | 0.85 | CCKBR (0.50) | CCKARCCKBRALDH1A1 | |
| SCHEMBL9646074 | 0.81 | CCKBR (0.44) | CCKARCCKBRLMNACYP3A4CYP2C9 | |
| SCHEMBL9558960 | 0.78 | CCKBR (0.46) | CCKARCCKBRALDH1A1 | |
| SCHEMBL9646121 | 0.77 | MMP2 (0.43) | CCKARCCKBRALDH1A1 | |
| SCHEMBL9644737 | 0.77 | THRA (0.46) | CCKARCCKBRTHRB | |
| Dexloxiglumide SCHEMBL366142 | 0.77 | CCKAR (1.00) | CCKARCCKBRLMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |