Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 6/20 | 0.32 |
| ▸ | WEE1 | P30291 | 2/20 | 0.31 |
| ▸ | MYT1 | Q01538 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10401596 | 0.99 | PKMYT1 (0.31) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL9647525 | 0.88 | P2RX3 (0.34) | — | |
| SCHEMBL9647120 | 0.86 | PRKCI (0.34) | — | |
| Hydrochloric Acid SCHEMBL10402300 | 0.85 | PRKCI (0.33) | — | |
| SCHEMBL10402416 | 0.84 | MAPT (0.39) | — | |
| SCHEMBL9648217 | 0.82 | PKMYT1 (0.34) | PKMYT1WEE1MYT1CDK1CREBBP | |
| Hydrochloric Acid SCHEMBL10401606 | 0.81 | PKMYT1 (0.33) | PKMYT1WEE1MYT1CDK1CREBBP | |
| SCHEMBL9646843 | 0.77 | PRKCI (0.35) | — | |
| SCHEMBL9645373 | 0.76 | NNMT (0.32) | PKMYT1 | |
| Mivazerol SCHEMBL8097939 | 0.76 | PARP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341231-B1 | SUBSTITUTED 1-(1H-IMIDAZOL-4-YL)ALKYL BENZAMIDES | U C B, S.A. (BE) | 1992-11-19 | — | — | EP | claimed |
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | claimed |
| EP-0341231-A1 | Substituted 1-(1H-imidazol-4-yl)alkyl benzamides | U C B, S.A. (BE) | 1989-11-08 | — | — | EP | claimed |
| EP-0341231-B1 | SUBSTITUTED 1-(1H-IMIDAZOL-4-YL)ALKYL BENZAMIDES | U C B, S.A. (BE) | 1992-11-19 | — | — | EP | disclosed |
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |
| EP-0341231-A1 | Substituted 1-(1H-imidazol-4-yl)alkyl benzamides | U C B, S.A. (BE) | 1989-11-08 | — | — | EP | disclosed |