Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 4/20 | 0.33 |
| ▸ | LDHB | P07195 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ME2 | P23368 | 1/20 | 0.30 |
| ▸ | ME1 | P48163 | 1/20 | 0.30 |
| ▸ | ME3 | Q16798 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646948 | 0.88 | PKMYT1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL10401596 | 0.87 | PKMYT1 (0.31) | — | |
| SCHEMBL9646843 | 0.86 | PRKCI (0.35) | P2RX3ME2ME1ME3 | |
| SCHEMBL10402416 | 0.85 | MAPT (0.39) | CYP3A4MAPT | |
| SCHEMBL9646806 | 0.81 | CA12 (0.32) | LDHALDHB | |
| SCHEMBL9647120 | 0.77 | PRKCI (0.34) | — | |
| SCHEMBL10401616 | 0.76 | CA12 (0.41) | MAPT | |
| Hydrochloric Acid SCHEMBL10402300 | 0.76 | PRKCI (0.33) | — | |
| SCHEMBL9648247 | 0.76 | ALDH1A1 (0.37) | NOTUMCYP3A4CYP2C9MAPTME2 | |
| SCHEMBL9518487 | 0.75 | HMGB1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341231-B1 | SUBSTITUTED 1-(1H-IMIDAZOL-4-YL)ALKYL BENZAMIDES | U C B, S.A. (BE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0341231-A1 | Substituted 1-(1H-imidazol-4-yl)alkyl benzamides | U C B, S.A. (BE) | 1989-11-08 | — | — | EP | disclosed |