Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902339 | 0.83 | MAPT (0.43) | KMT2AMAPTTDP1SMN1; SMN2PARP10 | |
| SCHEMBL30335696 | 0.82 | KMT2A (0.54) | KMT2AMAPTTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL30335504 | 0.82 | KMT2A (0.54) | KMT2AMAPTTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL9619082 | 0.82 | MAPT (0.40) | KMT2AMAPTALDH1A1PKMRAB9A | |
| SCHEMBL9646952 | 0.81 | MAPT (0.54) | KMT2AMAPTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL4635239 | 0.78 | HTR1A (0.38) | KMT2AALDH1A1L3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL8517516 | 0.78 | KMT2A (0.43) | KMT2AMAPTTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL6839788 | 0.77 | KMT2A (0.55) | KMT2AMAPTTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL130184 | 0.77 | PARP10 (0.57) | KMT2AMAPTTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL11449253 | 0.77 | RAB9A (0.56) | KMT2AALDH1A1PKMMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346756-B1 | PROCESS FOR PRODUCTION OF SULFONIUM COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-10-28 | — | — | EP | disclosed |
| US-5021197-A | Reacting a p-dialkylsulfoniophenol with a carbonyl halogenide in the presence of a secondary amine | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0346756-A1 | Process for production of sulfonium compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-12-20 | — | — | EP | disclosed |