Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576290 | 0.90 | ELANE (0.46) | MAPTPKMPOLBELANEBCHE | |
| SCHEMBL9646952 | 0.89 | MAPT (0.54) | MAPTPKMPOLBELANEKMT2A | |
| SCHEMBL9619081 | 0.88 | MAPT (0.37) | MAPTPKMPOLBELANEKMT2A | |
| SCHEMBL9487568 | 0.84 | THRB (0.44) | MAPTPKMPOLBELANEBCHE | |
| SCHEMBL11449253 | 0.84 | RAB9A (0.56) | PKMBCHEACHEKMT2ALMNA | |
| SCHEMBL9574184 | 0.82 | ELANE (0.51) | MAPTPKMPOLBELANEBCHE | |
| SCHEMBL9647013 | 0.82 | KMT2A (0.49) | MAPTPKMKMT2AALDH1A1RAB9A | |
| SCHEMBL9647538 | 0.80 | KMT2A (0.43) | MAPTKMT2ALMNAHTTALDH1A1 | |
| SCHEMBL30313539 | 0.80 | ELANE (0.48) | MAPTPKMPOLBELANEKMT2A | |
| SCHEMBL285230 | 0.79 | GAA (0.43) | PKMPOLBELANEKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4360865-A | — | — | None | — | — | JP | disclosed |
| JP-H04360865-A | SULFONIUM COMPOUND | SANSHIN CHEM IND CO LTD | 1992-12-14 | — | — | JP | disclosed |