Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647155 | 0.83 | KMT2A (0.53) | PDE4APDE4BPDE4CPDE4DPLA2G2A | |
| SCHEMBL9646337 | 0.83 | PARP1 (0.44) | MEN1LMNAMAPTKMT2APARP1 | |
| SCHEMBL31667524 | 0.80 | P2RX4 (0.49) | CHRM1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL31667699 | 0.74 | POLB (0.48) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9670940 | 0.70 | L3MBTL1 (0.65) | ACHEKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL266762 | 0.70 | GLS (0.51) | NR1H2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL4468997 | 0.70 | NR1H2 (0.44) | NR1H2L3MBTL1DTYMK | |
| SCHEMBL9647043 | 0.70 | GAA (0.44) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9647061 | 0.68 | L3MBTL1 (0.44) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL16137851 | 0.68 | NR1H2 (0.42) | NR1H2CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |