Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016087 | 0.91 | EGFR (0.64) | EGFRERBB2CA12CA9PRKCZ | |
| SCHEMBL9649398 | 0.86 | L3MBTL1 (0.73) | EGFRERBB2PRKCZL3MBTL1MAOB | |
| SCHEMBL9650265 | 0.82 | L3MBTL1 (0.74) | EGFRERBB2PRKCZL3MBTL1MAOB | |
| SCHEMBL3896190 | 0.80 | PRKCZ (0.82) | EGFRERBB2PRKCZL3MBTL1MAOB | |
| SCHEMBL27955196 | 0.78 | EGFR (0.71) | EGFRERBB2PRKCZL3MBTL1ATM | |
| SCHEMBL554670 | 0.77 | EGFR (0.74) | EGFRERBB2PRKCZL3MBTL1MAOB | |
| SCHEMBL27955192 | 0.77 | EGFR (0.58) | EGFRERBB2CA12CA9PRKCZ | |
| SCHEMBL9355978 | 0.76 | PDE5A (0.45) | EGFRERBB2CA12CA9ATM | |
| SCHEMBL9355980 | 0.76 | PDE5A (0.45) | EGFRERBB2CA12CA9ATM | |
| SCHEMBL9356235 | 0.75 | EGFR (1.00) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231835-B1 | ELECTRO PHOTOGRAPHIC RECORDING MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | claimed |
| US-4762760-A | FILM ON SUBSTRATE, ADHESION, FLEXIBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | claimed |
| EP-0231835-A2 | Electro photographic recording material | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-12 | — | — | EP | claimed |
| EP-0231835-B1 | ELECTRO PHOTOGRAPHIC RECORDING MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |
| US-4762760-A | FILM ON SUBSTRATE, ADHESION, FLEXIBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0231835-A2 | Electro photographic recording material | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-12 | — | — | EP | disclosed |