Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355980 | 1.00 | PDE5A (0.45) | PDE5AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL15024024 | 0.83 | MAPT (0.45) | PDE5AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4410072 | 0.83 | MAPT (0.45) | PDE5AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9648974 | 0.81 | L3MBTL1 (0.43) | PDE5AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9648922 | 0.76 | EGFR (0.64) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL28016087 | 0.71 | EGFR (0.64) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL2254665 | 0.70 | CA1 (0.52) | MEN1LMNAKMT2AATMEGFR | |
| SCHEMBL9359546 | 0.67 | MEN1 (0.51) | PDE5AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9359540 | 0.67 | MEN1 (0.51) | PDE5AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL2253754 | 0.67 | NFE2L2 (0.49) | KDM4EMEN1ALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451561-B1 | Photopolymerisable mixture and recording material made from it | MORTON INT INC (US) | 1994-11-09 | — | — | EP | disclosed |
| US-5221595-A | Printing plates, photoresist; high photosensitivity, acid resistance | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0451561-A1 | Photopolymerisable mixture and recording material made from it | MORTON INTERNATIONAL, INC. (US) | 1991-10-16 | — | — | EP | disclosed |