Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648845 | 0.85 | — | — | |
| SCHEMBL9649290 | 0.85 | ACHE (0.31) | — | |
| SCHEMBL9650453 | 0.83 | — | — | |
| SCHEMBL9649355 | 0.82 | APP (0.35) | — | |
| SCHEMBL9650104 | 0.82 | — | — | |
| SCHEMBL9649272 | 0.79 | KDM5B (0.31) | — | |
| SCHEMBL9649284 | 0.77 | CCNB2 (0.36) | — | |
| SCHEMBL9646840 | 0.75 | TRPV3 (0.37) | — | |
| SCHEMBL9648726 | 0.75 | GABRG2 (0.33) | — | |
| SCHEMBL9648860 | 0.74 | CCNB2 (0.37) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120848-A | Anticholesterol and antilipemic agents; hydroxy-3-methylglutaryl/3-/ coenzyme A reductase inhibitors | GLAXO GROUP LIMITED (GB) | 1992-06-09 | — | — | US | disclosed |
| US-5013749-A | Imidazole derivatives and their use as hypercholesterolemia and hyperlipoproteinemia agents | GLAXO GROUP LIMITED (GB) | 1991-05-07 | — | — | US | disclosed |