Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646840 | 0.86 | TRPV3 (0.37) | TRPV3 | |
| SCHEMBL9649284 | 0.85 | CCNB2 (0.36) | TRPV3 | |
| SCHEMBL9650453 | 0.84 | — | — | |
| SCHEMBL9649043 | 0.82 | PTGS2 (0.34) | — | |
| SCHEMBL9650104 | 0.81 | — | — | |
| SCHEMBL9648845 | 0.81 | — | — | |
| SCHEMBL9649272 | 0.78 | KDM5B (0.31) | CYP1A2CYP2C19 | |
| SCHEMBL9649290 | 0.77 | ACHE (0.31) | — | |
| SCHEMBL9646804 | 0.76 | IDO1 (0.33) | — | |
| SCHEMBL28360893 | 0.74 | L3MBTL1 (0.35) | APPCYP1A2CYP2C19AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120848-A | Anticholesterol and antilipemic agents; hydroxy-3-methylglutaryl/3-/ coenzyme A reductase inhibitors | GLAXO GROUP LIMITED (GB) | 1992-06-09 | — | — | US | disclosed |