Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16353682 | 0.82 | TSHR (0.55) | TSHRHTR1AHTR7ATMKDM4E | |
| SCHEMBL10975718 | 0.82 | L3MBTL1 (0.55) | TSHRHTR1AHTR7ATMKDM4E | |
| SCHEMBL18909220 | 0.81 | TSHR (0.49) | TSHRHTR1AHTR7KDM4EHSD11B1 | |
| SCHEMBL9633178 | 0.79 | GNAI3 (0.61) | TSHRHTR1AHTR7MEN1KMT2A | |
| SCHEMBL26270305 | 0.78 | TSHR (0.48) | TSHRHTR1AHTR7ATMKDM4E | |
| SCHEMBL12424660 | 0.78 | TSHR (0.54) | TSHRHTR1AHTR7KDM4EHSD11B1 | |
| SCHEMBL12766885 | 0.78 | TSHR (0.58) | TSHRHTR1AHTR7KDM4EHSD11B1 | |
| SCHEMBL9633474 | 0.78 | L3MBTL1 (0.63) | TSHRHTR1AHTR7ATMMEN1 | |
| SCHEMBL14012786 | 0.77 | TSHR (0.51) | TSHRHTR1AHTR7KDM4EHSD11B1 | |
| SCHEMBL18928680 | 0.75 | ATM (0.71) | ATMNPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368763-B1 | 4-MERCAPTO BUTYRAMIDES N-MONO OR N,N-DISUBSTITUTED BY A MONO OR POLYHYDROXYALKYL RADICAL, AND THEIR USE AS REDUCING AGENTS IN THE PROCESS OF PERMANENT DEFORMATION OF THE HAIR | L'OREAL (FR) | 1992-10-14 | — | — | EP | claimed |