Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646921 | 0.75 | EIF2S1 (0.40) | EIF2AK3KDM4ESMN1; SMN2EIF2S1ALOX5AP | |
| SCHEMBL17055207 | 0.72 | HDAC1 (0.64) | HDAC1HDAC6GABRPGABRDGABRA1 | |
| SCHEMBL9769230 | 0.72 | ADRB2 (0.51) | KDM4ESMN1; SMN2 | |
| SCHEMBL9649808 | 0.72 | ADRB2 (0.37) | EIF2AK3KDM4EHSD17B10SMN1; SMN2EIF2S1 | |
| SCHEMBL9769240 | 0.72 | ADRB2 (0.51) | KDM4ESMN1; SMN2 | |
| SCHEMBL28599560 | 0.71 | HDAC3 (0.47) | KDM4EHDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL12669776 | 0.71 | LMNA (0.54) | KDM4EHDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL12669773 | 0.71 | LMNA (0.54) | KDM4EHDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL10688938 | 0.71 | LMNA (0.54) | KDM4EHDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL6469008 | 0.70 | NOS3 (0.46) | KDM4EHSD17B10HDAC1HDAC6GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |