Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.33 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.32 |
| ▸ | FEN1 | P39748 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17273620 | 0.81 | RAB9A (0.41) | KDM4ERAB9AALDH1A1NPC1TP53 | |
| SCHEMBL10360151 | 0.80 | ALDH1A1 (0.37) | ADRB2ADRB1ADRB3PTGS1ACKR3 | |
| SCHEMBL22556882 | 0.78 | ADRA2A (0.41) | PTGS1KDM4ERAB9ACA12CA1 | |
| SCHEMBL9649660 | 0.73 | MAPK1 (0.33) | ADRB2ADRB1ADRB3KDM4EPOLB | |
| SCHEMBL10361058 | 0.72 | LMNA (0.50) | ADRB2ADRB1ADRB3KDM4ECASP7 | |
| SCHEMBL9649692 | 0.72 | EIF2AK3 (0.41) | EIF2S1EIF2AK3ALOX5APFEN1KDM4E | |
| SCHEMBL22556951 | 0.70 | ADRA2A (0.39) | KDM4ERAB9APOLBCA12CA1 | |
| SCHEMBL9648708 | 0.70 | LMNA (0.39) | ADRB2ADRB1KDM4EPOLBCA1 | |
| SCHEMBL20686287 | 0.69 | KDM4E (0.37) | KDM4ERAB9APOLBCA12CA1 | |
| SCHEMBL10361056 | 0.69 | ADRB2 (0.39) | ADRB2ADRB1KDM4ERAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |