SCHEMBL9649698

SCHEMBL9649698

Cc1c(S(C)(=O)=O)ccc(C(=O)Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
F10 P00742 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.34
CCR2 P41597 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4032987 0.86 LMNA (0.45) ALDH1A1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL4034288 0.86 ALDH1A1 (0.39) ALDH1A1F10L3MBTL1LMNACCR2
SCHEMBL31223256 0.86 ALDH1A1 (0.39) ALDH1A1F10L3MBTL1LMNACCR2
SCHEMBL9761613 0.85 ALDH1A1 (0.38) ALDH1A1L3MBTL1LMNACYP1A2CYP3A4
SCHEMBL6101293 0.85 CYP1A2 (0.41) ALDH1A1LMNACYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL9649707 0.84 LMNA (0.44) ALDH1A1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL4268094 0.81 KDM4E (0.44) ALDH1A1L3MBTL1LMNAMAPTHPGD
SCHEMBL28324465 0.81 MAPT (0.34) ALDH1A1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL28176076 0.80 BCAT2 (0.44) ALDH1A1LMNACCR2CYP1A2CYP3A4
SCHEMBL21179401 0.79 TSHR (0.46) ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113387942-A Pyrazole carboxylic ester compound and application thereof 沈阳中化农药化工研发有限公司 2021-09-14 CN disclosed
US-5145502-A Sulfur containing NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-09-08 US disclosed
US-5132434-A Contain thiophene or thiopyran ring NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-07-21 US disclosed