Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647803 | 0.90 | PTPN11 (0.46) | THRATHRBMAPTFAAHALDH1A1 | |
| SCHEMBL9651201 | 0.83 | PTPN11 (0.57) | MAPTALDH1A1PTPN11PDE4APDE4B | |
| SCHEMBL9649896 | 0.81 | ALDH1A1 (0.56) | MAPTALDH1A1 | |
| SCHEMBL13029245 | 0.81 | MAPT (0.41) | THRATHRBMAPTALDH1A1ESR1 | |
| SCHEMBL8363894 | 0.79 | THRA (0.45) | THRAALDH1A1TSHR | |
| SCHEMBL8362473 | 0.79 | THRA (0.45) | THRAALDH1A1TSHR | |
| SCHEMBL10527333 | 0.79 | RARB (0.49) | THRATHRBMAPTTSHRPTPN11 | |
| SCHEMBL12286950 | 0.79 | RARB (0.49) | THRATHRBMAPTTSHRPTPN11 | |
| SCHEMBL9149901 | 0.78 | MAPT (0.49) | THRATHRBMAPTALDH1A1PTPN11 | |
| SCHEMBL9510882 | 0.78 | PDE4A (0.44) | THRATHRBMAPTALDH1A1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267670-B1 | OPTICALLY ACTIVE LIQUID CRYSTAL COMPOUND HAVING CYANO GROUP | Chisso Corporation (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-4886622-A | Optically active liquid crystal compound having cyano group | CHISSO CORPORATION (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0267670-A1 | Optically active liquid crystal compound having cyano group | Chisso Corporation (JP) | 1988-05-18 | — | — | EP | disclosed |