Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9793431 | 0.86 | HTR6 (0.62) | HTR6KMT2ATSHRHTTKDM4E | |
| SCHEMBL8427241 | 0.85 | HTR6 (0.46) | HTR6KMT2APTGS2HTTALDH1A1 | |
| SCHEMBL10438260 | 0.81 | MAOB (0.47) | HTR6PTGS2MAPTPOLB | |
| Biphenyl SCHEMBL28423764 | 0.79 | HTR6 (0.65) | HTR6KMT2ATSHRHTTKDM4E | |
| SCHEMBL27723037 | 0.77 | HTR6 (0.52) | HTR6KMT2ATSHRHTTKDM4E | |
| SCHEMBL8844836 | 0.76 | HTR6 (0.55) | HTR6KMT2APTGS2TSHRHTT | |
| SCHEMBL9242466 | 0.76 | HTR6 (0.55) | HTR6KMT2APTGS2TSHRHTT | |
| SCHEMBL9323437 | 0.76 | HTR6 (0.65) | HTR6KMT2APTGS2HTTMAPT | |
| SCHEMBL7187841 | 0.75 | HTR6 (0.64) | HTR6KMT2ATSHRHTTALDH1A1 | |
| SCHEMBL10342789 | 0.75 | HTR6 (0.65) | HTR6KMT2ATSHRHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243997-B1 | PREPARATION OF POLY (ARYLENE ETHER KETONES) | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1992-10-14 | — | — | EP | claimed |
| EP-0124276-B1 | PREPARATION OF AROMATIC POLYMERS | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1989-03-22 | — | — | EP | claimed |