Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 8/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434434 | 1.00 | FKBP1A (0.52) | FKBP1ARAB9AACERENLMNA | |
| SCHEMBL3154647 | 1.00 | FKBP1A (0.52) | FKBP1ARAB9AACERENLMNA | |
| SCHEMBL1774605 | 0.95 | FKBP1A (0.58) | FKBP1ARAB9AACERENLMNA | |
| SCHEMBL7551999 | 0.89 | FKBP1A (0.45) | FKBP1ARAB9AACERENLMNA | |
| SCHEMBL20253015 | 0.86 | FKBP1A (0.51) | FKBP1ARAB9AHSD17B10 | |
| SCHEMBL2006947 | 0.86 | FKBP1A (0.58) | FKBP1ARAB9ALMNAPEPDALDH1A1 | |
| SCHEMBL9169937 | 0.81 | RAB9A (0.61) | RAB9AACERENLMNAHSD17B10 | |
| SCHEMBL31257712 | 0.81 | RAB9A (0.61) | RAB9AACERENLMNAHSD17B10 | |
| SCHEMBL9169924 | 0.81 | RAB9A (0.61) | RAB9AACERENLMNAHSD17B10 | |
| SCHEMBL21296651 | 0.81 | RAB9A (0.54) | FKBP1ARAB9AACERENLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517792-A1 | TERMINALLY BLOCKED ANTIVIRAL PEPTIDES | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1992-12-16 | — | — | EP | disclosed |
| WO-1991013088-A1 | TERMINALLY BLOCKED ANTIVIRAL PEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-09-05 | — | — | WO | disclosed |