Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613368 | 0.92 | ALDH1A1 (0.52) | MAPTRAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL11614827 | 0.90 | RAB9A (0.58) | MAPTRAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL11616952 | 0.89 | MAPT (0.60) | MAPTRAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL11614525 | 0.89 | MAPT (0.60) | MAPTRAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL9694662 | 0.88 | RARB (0.55) | MAPTRAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL11755996 | 0.88 | MAPT (0.59) | MAPTRAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL19737251 | 0.83 | CA12 (0.58) | MAPTRAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL4949564 | 0.82 | POLB (0.54) | MAPTRAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL4636262 | 0.82 | FOS (0.54) | MAPTRAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL9879844 | 0.82 | ALDH1A1 (0.43) | MAPTRAB9ANPC1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112523-A | High clearing point for liquid crystal displays | CHISSO CORPORATION (JP) | 1992-05-12 | — | — | US | disclosed |
| US-4874546-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1989-10-17 | — | — | US | disclosed |
| US-4066570-A | OPTICAL CELLS, NEMATIC MIXTURES, LIQUID CRYSTALS | HOFFMAN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-3997536-A | LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1976-12-14 | — | — | US | disclosed |