Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994122 | 0.80 | MEN1 (0.52) | SIGMAR1 | |
| SCHEMBL222192 | 0.79 | ACHE (0.65) | SIGMAR1ACHE | |
| Hydrochloric Acid SCHEMBL11310118 | 0.78 | CCR3 (0.69) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL784863 | 0.78 | SIGMAR1 (0.68) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9651228 | 0.77 | SIGMAR1 (0.61) | SIGMAR1DRD2KCNH2 | |
| SCHEMBL9030647 | 0.77 | SIGMAR1 (0.67) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL11803527 | 0.76 | POLB (0.48) | — | |
| SCHEMBL27473621 | 0.76 | SIGMAR1 (0.65) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL11313073 | 0.76 | SIGMAR1 (0.65) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7475791 | 0.75 | ALDH1A1 (0.59) | SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |