Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL965196

CC1(C)C(N)CC1C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 3/20 0.35
OAT P04181 1/20 0.34
SLC1A1 P43005 1/20 0.33
GRM2 Q14416 1/20 0.32
GABRR1 P24046 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15362631 0.88 GABRR1 (0.39) SLC1A2SLC1A1GABRR1SLC6A4
SCHEMBL2178920 0.88 GABRR1 (0.39) SLC1A2SLC1A1GABRR1SLC6A4
Hydrochloric Acid SCHEMBL16669413 0.86 SLC1A2 (0.37) SLC1A2SLC1A1GABRR1SLC6A4
Trifluoroacetic Acid SCHEMBL1006153 0.74 HSD11B1 (0.40)
SCHEMBL965198 0.74
SCHEMBL16822029 0.71 GAA (0.31)
SCHEMBL12914984 0.71 CD81 (0.32)
SCHEMBL12914987 0.71 CD81 (0.32)
SCHEMBL6121809 0.70 APLNR (0.42) SLC1A2SLC1A1GABRR1SLC6A4
SCHEMBL15352277 0.70 APLNR (0.42) SLC1A2SLC1A1GABRR1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9067966-B2 Lupeol-type triterpene derivatives as antivirals HETERO RESEARCH FOUNDATION, HETERO DRUGS LTD. (IN) 2015-06-30 US disclosed
EP-2454270-B1 LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS HETERO RESEARCH FOUNDATION (IN) 2015-02-11 EP disclosed
EP-2454270-A2 LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS Hetero Research Foundation (IN) 2012-05-23 EP disclosed
WO-2011007230-A2 LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS HETERO RESEARCH FOUNDATION (IN) 2011-01-20 WO disclosed
US-20110015196-A1 LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS HETERO RESEARCH FOUNDATION (IN) 2011-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015196-A1 LUPEOL-TYPE TRITERPENE DERIVATIVES AS ANTIVIRALS MAVS, IRF3, LSS SLC1A2 4703/4885OAT 739/4885SLC1A1 4458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.