Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651778 | 0.81 | KMT2A (0.40) | ALDH1A1LMNAEGFRALKNPC1 | |
| SCHEMBL9653264 | 0.74 | KDM4E (0.32) | ALDH1A1LMNATSHRMEN1MAPT | |
| SCHEMBL9652739 | 0.73 | ALDH1A1 (0.33) | ALDH1A1KMT2AKDM4E | |
| SCHEMBL23021682 | 0.71 | ALDH1A1 (0.51) | ALDH1A1LMNASLC6A4NPC1RAB9A | |
| SCHEMBL4243790 | 0.71 | PTGS2 (0.48) | ALDH1A1LMNASLC6A4NPC1TSHR | |
| SCHEMBL29800289 | 0.71 | PTGS2 (0.48) | ALDH1A1LMNASLC6A4NPC1TSHR | |
| SCHEMBL21835003 | 0.70 | ALDH1A1 (0.33) | ALDH1A1LMNASLC6A4TSHRMEN1 | |
| SCHEMBL9652720 | 0.70 | LMNA (0.33) | ALDH1A1LMNATSHRMAPTKDM4E | |
| SCHEMBL9653700 | 0.69 | CYP1A2 (0.36) | ALDH1A1NPC1TSHRRAB9AMEN1 | |
| SCHEMBL108571 | 0.69 | TSHR (0.52) | ALDH1A1LMNATSHRSMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213892-B1 | HERBICIDALLY ACTIVE ENOLS | ROHM AND HAAS COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4781750-A | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0213892-A2 | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |