Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073141 | 0.81 | CYP2C9 (0.47) | LMNASMN1; SMN2PKML3MBTL1MAPT | |
| Butane SCHEMBL7456611 | 0.74 | EPHX1 (0.46) | LMNAMAPTALDH1A1 | |
| SCHEMBL9638237 | 0.71 | CA1 (0.34) | MAPT | |
| SCHEMBL767298 | 0.68 | ESR1 (0.40) | LMNAMAPK1POLBGAA | |
| SCHEMBL9637973 | 0.67 | HPN (0.47) | SMN1; SMN2L3MBTL1POLBMAPTTDP1 | |
| SCHEMBL15572456 | 0.67 | HPGD (0.35) | SMN1; SMN2MAPK1FFAR1MAPTHPGD | |
| SCHEMBL64260 | 0.67 | LMNA (0.41) | LMNAMAPK1POLBALDH1A1 | |
| SCHEMBL15572774 | 0.67 | HPGD (0.35) | SMN1; SMN2MAPK1FFAR1MAPTHPGD | |
| SCHEMBL5745420 | 0.67 | LMNA (0.41) | LMNAMAPK1POLBALDH1A1 | |
| SCHEMBL15572570 | 0.67 | HPGD (0.35) | SMN1; SMN2L3MBTL1MAPK1POLBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339237-B1 | PHENOL SUBSTITUTED GEM-DIPHOSPHONATE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1992-12-30 | — | — | EP | claimed |