Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 12/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638237 | 0.79 | CA1 (0.34) | MAPTCA2CA1MEN1KMT2A | |
| SCHEMBL10503818 | 0.74 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5CA2 | |
| SCHEMBL10698130 | 0.74 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5CA2 | |
| SCHEMBL646923 | 0.72 | ALOX15 (0.61) | HPNMAPTALOX15SIRT5CA2 | |
| SCHEMBL9504462 | 0.72 | ALOX15 (0.61) | HPNMAPTALOX15SIRT5CA2 | |
| SCHEMBL4951465 | 0.71 | HMGCR (0.40) | HPNMAPTALOX15SIRT5CA2 | |
| SCHEMBL2279291 | 0.71 | HMGCR (0.52) | MAPTALOX15CA2CA1SMN1; SMN2 | |
| SCHEMBL9276507 | 0.71 | CA2 (0.39) | HPNMAPTALOX15SIRT5CA2 | |
| SCHEMBL10963673 | 0.70 | HPN (0.53) | HPNMAPTALOX15SIRT5CA2 | |
| SCHEMBL698499 | 0.70 | CA2 (0.45) | HPNMAPTALOX15SIRT5CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153183-A | Antiarthritic agents | TORAY INDUSTRIES, INC. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0440809-A1 | METHYLENEDIPHOSPHONIC ACID COMPOUND AND ANTI-INFLAMMATORY CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 1991-08-14 | — | — | EP | disclosed |