Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.72 |
| ▸ | HTR1A | P08908 | 5/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | DRD3 | P35462 | 3/20 | 0.70 |
| ▸ | DRD4 | P21917 | 4/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652828 | 0.93 | DRD2 (0.81) | DRD2HTR1AADRA1ADRD3DRD4 | |
| SCHEMBL7703066 | 0.87 | DRD2 (0.85) | DRD2HTR1AADRA1ADRD3DRD4 | |
| SCHEMBL6596142 | 0.84 | HTR1A (1.00) | HTR1A | |
| SCHEMBL10911336 | 0.84 | DRD2 (1.00) | DRD2HTR1AADRA1ADRD3DRD4 | |
| SCHEMBL9652768 | 0.84 | ALDH1A1 (0.63) | DRD2HTR1AADRA1ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL6599417 | 0.82 | HTR1A (0.96) | HTR1A | |
| SCHEMBL14761584 | 0.81 | DRD2 (0.94) | DRD2HTR1AADRA1ADRD3DRD4 | |
| SCHEMBL9650932 | 0.80 | ADRA1A (0.70) | DRD2HTR1AADRA1ADRD4 | |
| SCHEMBL3966648 | 0.80 | HTR1A (1.00) | DRD2HTR1AADRA1ADRD4 | |
| SCHEMBL10911858 | 0.80 | DRD2 (0.85) | DRD2HTR1AADRA1ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496692-A1 | 2-Methoxyphenylpiperazine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-07-29 | — | — | EP | claimed |