Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28004213 | 0.78 | NPC1 (0.47) | MAPTLMNANPC1RAB9A | |
| Methacrylic Acid SCHEMBL9652589 | 0.75 | MAPT (0.43) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2701708 | 0.74 | SIGMAR1 (0.48) | — | |
| Diphenylamine SCHEMBL29875738 | 0.74 | MAPT (0.61) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10448750 | 0.71 | BRS3 (0.44) | — | |
| SCHEMBL8148623 | 0.70 | MAPT (0.46) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16521514 | 0.70 | MAPT (0.53) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1839615 | 0.70 | SLC6A2 (0.50) | ALDH1A1LMNA | |
| SCHEMBL15899528 | 0.70 | LMNA (0.45) | KMT2ALMNAMAPK1ACACB | |
| SCHEMBL10595150 | 0.70 | CASP3 (0.53) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155148-A | For stabilizing oxidizable rubbers, oils; co-polymerizable through unsaturated site | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0420790-A1 | Ester derivatives from p-hydroxydiphenylamine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |