Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650689 | 0.78 | ALDH1A1 (0.45) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11069028 | 0.76 | ALDH1A1 (0.43) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24611536 | 0.74 | ALDH1A1 (0.45) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| Sulfur Dioxide SCHEMBL11107367 | 0.73 | ALDH1A1 (0.39) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9650735 | 0.72 | ELANE (0.41) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14301059 | 0.69 | ALDH1A1 (0.50) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10936301 | 0.68 | ALDH1A1 (0.54) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| Hexane SCHEMBL11060778 | 0.68 | PTGS2 (0.41) | ALDH1A1HPGDLMNA | |
| Benzophenone SCHEMBL27919557 | 0.65 | ALDH1A1 (0.70) | KMT2AMEN1TSHRNPC1RAB9A | |
| SCHEMBL9792276 | 0.65 | ALDH1A1 (0.50) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480465-A2 | Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1,-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1992-04-15 | — | — | EP | disclosed |