Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902708 | 1.00 | ADRB1 (0.49) | ADRB1OPRK1ADRB2HTR1AALDH1A1 | |
| SCHEMBL4902703 | 1.00 | ADRB1 (0.49) | ADRB1OPRK1ADRB2HTR1AALDH1A1 | |
| SCHEMBL8054602 | 0.93 | ALDH1A1 (0.46) | ADRB1OPRK1ADRB2HTR1AALDH1A1 | |
| SCHEMBL9386670 | 0.88 | DRD2 (0.51) | ADRB1OPRK1ADRB2HTR1AALDH1A1 | |
| SCHEMBL7134153 | 0.88 | DRD2 (0.51) | ADRB1OPRK1ADRB2HTR1AALDH1A1 | |
| SCHEMBL10593293 | 0.79 | ALDH1A1 (0.41) | ADRB1OPRK1ADRB2HTR1AALDH1A1 | |
| SCHEMBL9389280 | 0.79 | ADRB1 (0.52) | ADRB1OPRK1ADRB2HTR1ADRD2 | |
| SCHEMBL1764193 | 0.79 | ADRB2 (0.57) | ADRB1OPRK1ADRB2HTR1ATP53 | |
| SCHEMBL11548407 | 0.78 | ALDH1A1 (0.47) | ADRB2HTR1AALDH1A1GLATP53 | |
| SCHEMBL9384498 | 0.77 | ALDH1A1 (0.46) | ADRB1OPRK1ADRB2HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |