Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 5/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 5/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 4/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 4/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654002 | 0.75 | KIF11 (0.46) | KIF11KCNN4MEN1KMT2ALMNA | |
| SCHEMBL12264129 | 0.71 | KIF11 (0.61) | KIF11KCNN4SIGMAR1 | |
| SCHEMBL4199968 | 0.69 | KCNN4 (0.56) | KIF11KCNN4MEN1KMT2ATDP1 | |
| SCHEMBL147990 | 0.67 | KIF11 (0.65) | KIF11KCNN4MEN1KMT2ATDP1 | |
| SCHEMBL22919848 | 0.67 | KIF11 (0.55) | KIF11KCNN4SIGMAR1 | |
| SCHEMBL10065920 | 0.65 | KCNN4 (0.60) | KIF11KCNN4ALDH1A1ALOX15TSHR | |
| SCHEMBL17875119 | 0.65 | KIF11 (0.44) | KIF11KCNN4KMT2ALMNAALDH1A1 | |
| SCHEMBL27189892 | 0.65 | KIF11 (0.45) | KIF11KCNN4MEN1KMT2ATDP1 | |
| SCHEMBL28544425 | 0.65 | KCNN4 (0.55) | KIF11KCNN4KMT2ALMNAALDH1A1 | |
| SCHEMBL9926038 | 0.64 | KIF11 (0.67) | KIF11KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554648-A | NITROGEN MUSTARD ALKYLATING AGENTS | WARNER LAMBERT COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| US-5348977-A | Cobalt complexes as anti-cancer agents | WARNER LAMBERT COMPANY (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0496641-A2 | Cobalt complexes as anticancer agents | WARNER-LAMBERT COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |