Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154470 | 0.82 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 | |
| SCHEMBL9654019 | 0.82 | FFAR1 (0.43) | — | |
| SCHEMBL1154276 | 0.78 | LMNA (0.56) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 | |
| SCHEMBL11406933 | 0.78 | KDM4E (0.50) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 | |
| SCHEMBL1153371 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 | |
| SCHEMBL31259495 | 0.74 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 | |
| SCHEMBL16638539 | 0.74 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 | |
| SCHEMBL3748894 | 0.74 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 | |
| SCHEMBL8635319 | 0.74 | RAB9A (0.66) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 | |
| SCHEMBL11360493 | 0.73 | SMN1; SMN2 (0.71) | CYP1A2CYP3A4CYP2C19HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263438-B1 | BENZOYLUREA COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-4985449-A | N-benzoyl-N-pyridyloxy phenyl urea compounds and pesticide compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4861799-A | INSSECTICIDES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0263438-A2 | Benzoylurea compounds, process for their production and pesticides containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1988-04-13 | — | — | EP | disclosed |