Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384498 | 0.87 | ALDH1A1 (0.46) | ALDH1A1GLATDP1HTR2ASLC6A4 | |
| SCHEMBL9652974 | 0.86 | ALDH1A1 (0.38) | ALDH1A1GLATDP1HTR2ASLC6A4 | |
| SCHEMBL9651024 | 0.86 | HTR2A (0.44) | ALDH1A1GLATDP1HTR2ASLC6A4 | |
| SCHEMBL9385939 | 0.86 | ALDH1A1 (0.41) | ALDH1A1GLATDP1HTR2ASLC6A4 | |
| SCHEMBL9384482 | 0.83 | ALDH1A1 (0.36) | ALDH1A1GLATDP1HTR2ASLC6A4 | |
| SCHEMBL11381634 | 0.83 | ALDH1A1 (0.39) | ALDH1A1GLATDP1HTR2ASLC6A4 | |
| SCHEMBL11380495 | 0.83 | ALDH1A1 (0.36) | ALDH1A1GLATDP1HTR2ASLC6A4 | |
| SCHEMBL11378856 | 0.82 | ALDH1A1 (0.35) | ALDH1A1GLATDP1HTR2ASLC6A4 | |
| SCHEMBL7091814 | 0.81 | BRD4 (0.42) | ALDH1A1GLATDP1 | |
| SCHEMBL9534845 | 0.81 | VDR (0.41) | ALDH1A1GLATDP1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |