Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19836840 | 0.82 | DYRK1A (0.55) | PARP1ARDYRK1A | |
| SCHEMBL19836839 | 0.82 | DYRK1A (0.55) | CYP1A2TSHRALDH1A1ARDYRK1A | |
| SCHEMBL21623871 | 0.82 | BRPF1 (0.58) | HPGDCYP1A2MAPTTSHRALDH1A1 | |
| SCHEMBL5266825 | 0.82 | IMPDH2 (0.50) | HPGDHSD17B10TDP1ALOX15RECQL | |
| SCHEMBL28393497 | 0.81 | ASH1L (0.48) | TDP1MAPTTSHRALDH1A1LMNA | |
| SCHEMBL21754248 | 0.79 | DYRK1A (0.44) | HPGDHSD17B10TDP1ALOX15RECQL | |
| SCHEMBL5248011 | 0.79 | ATM (0.48) | HPGDHSD17B10TDP1ALOX15RECQL | |
| SCHEMBL6498006 | 0.79 | HPGD (0.38) | HPGDHSD17B10TDP1ALOX15RECQL | |
| SCHEMBL20673987 | 0.78 | KDM4E (0.56) | HPGDHSD17B10ALOX15RECQLCYP1A2 | |
| SCHEMBL20673988 | 0.78 | KIF11 (0.47) | HSD17B10TDP1ALOX15CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271186-B1 | HYDROXYINDOLES AND THEIR USE IN DYEING | REPLIGEN CORPORATION (US) | 1992-12-30 | — | — | EP | claimed |
| CN-100475814-C | 7-azaindoles and their use as therapeutic agents | ELBION AG (DE) | 2009-04-08 | — | — | CN | disclosed |
| CN-1805960-A | 7-azaindoles and their use as therapeutic agents | ELBION AG (DE) | 2006-07-19 | — | — | CN | disclosed |
| CN-1777600-A | 4-, 6-or 7-hydroxyindoles having N-oxide groups and their use as therapeutic agents | ELBION AG (DE) | 2006-05-24 | — | — | CN | disclosed |
| CN-1777599-A | 5-hydroxyindoles having N-oxide groups and their use as phosphodiesterase 4 inhibitors | ELBION AG (DE) | 2006-05-24 | — | — | CN | disclosed |
| CN-1711082-A | Novel hydroxyindoles, their use as phosphodiesterase 4 inhibitors and process for their preparation | ELBION AG (DE) | 2005-12-21 | — | — | CN | disclosed |
| CN-1051727-A | Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| CN-1051727-A | Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |