Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.55 |
| ▸ | CLK1 | P49759 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654333 | 0.82 | HPGD (0.42) | DYRK1APARP1AR | |
| SCHEMBL1137500 | 0.75 | DYRK1A (0.55) | DYRK1ACLK1CDK5CDK5R1GSK3B | |
| SCHEMBL13544614 | 0.75 | DYRK1A (0.55) | DYRK1ACLK1CDK5CDK5R1GSK3B | |
| SCHEMBL31049262 | 0.75 | DYRK1A (0.55) | DYRK1ACLK1CDK5CDK5R1GSK3B | |
| SCHEMBL5266825 | 0.75 | IMPDH2 (0.50) | CLK1CDK5CDK5R1PARP1 | |
| SCHEMBL24743296 | 0.75 | DYRK1A (0.55) | DYRK1ACLK1CDK5CDK5R1GSK3B | |
| SCHEMBL31188784 | 0.75 | DYRK1A (0.55) | DYRK1ACLK1CDK5CDK5R1GSK3B | |
| SCHEMBL21636392 | 0.75 | DYRK1A (0.55) | DYRK1ACLK1CDK5CDK5R1GSK3B | |
| SCHEMBL21623871 | 0.75 | BRPF1 (0.58) | AHRAR | |
| SCHEMBL19836839 | 0.75 | DYRK1A (0.55) | DYRK1ASLC6A4AHRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12098405-B2 | Protecting group chemistry for clean, reductant-free dyeing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-09-24 | — | — | US | disclosed |
| US-20220136024-A1 | PROTECTING GROUP CHEMISTRY FOR CLEAN, REDUCTANT-FREE DYEING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-05-05 | — | — | US | disclosed |
| US-11203774-B2 | Protecting group chemistry for clean, reductant-free dyeing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-21 | — | — | US | disclosed |
| US-20200325516-A1 | PROTECTING GROUP CHEMISTRY FOR CLEAN, REDUCTANT-FREE DYEING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-10-15 | — | — | US | disclosed |
| US-10704070-B2 | Protecting group chemistry for clean, reductant-free dyeing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-07 | — | — | US | disclosed |
| US-20180037917-A1 | PROTECTING GROUP CHEMISTRY FOR CLEAN, REDUCTANT-FREE DYEING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-08 | — | — | US | disclosed |