Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | UBE2I | P63279 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655222 | 1.00 | CDC25B (0.35) | CDC25BUBE2ISAE1UBA2KDM1A | |
| SCHEMBL10570029 | 0.90 | — | — | |
| SCHEMBL9655492 | 0.81 | HTT (0.38) | KDM1AMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9655498 | 0.81 | HTT (0.38) | KDM1AMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9655433 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL9655439 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL9652865 | 0.71 | RAB9A (0.44) | MEN1KMT2A | |
| SCHEMBL9652870 | 0.71 | RAB9A (0.44) | MEN1KMT2A | |
| SCHEMBL9655211 | 0.70 | ACHE (0.43) | MEN1KMT2AGAA | |
| SCHEMBL9655205 | 0.70 | ACHE (0.43) | MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099016-A | Mitomycin analogs containing 7-alkoxy groups and disulfides as antibiotics | BRISTOL-MYERS COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5097036-A | Mitomycin analogs; antibiotics antitumor agents | BRISTOL-MYERS COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4927943-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1990-05-22 | — | — | US | disclosed |